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I actually was constipated after my 3rd but didn't think anything of it. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. (A generic drug is an exact copy of the active drug in a brand-name medication.) (Hemoglobin is a protein thats found in red blood cells.). Available for Android and iOS devices. But the length of time that this may take varies from person to person. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. 2023 Medicine.com All rights reserved. <> People with IDA have low blood levels of hemoglobin. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. You may report side effects to FDA at 1-800-FDA-1088. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. ByDr. reactions at the site of the injection. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. With IV infusion, the drug is given as a slow drip into your vein over a period of time. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Mild side effects of Injectafer can include:*. A shortage of iron can cause health problems. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. We cancelled my 5th because of the reaction. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. As with most drugs, some people can have an allergic reaction after taking Injectafer. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Its not known if Injectafer is safe to take during pregnancy. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Does Venofer Vial interact with other medications? To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. Can diet help improve depression symptoms? But you likely wont feel the drug working inside of you. intense abdominal pain. generalized weakness. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Call your doctor right away if you have serious side effects. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. Nausea. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Do not double the dose to catch up. Why is the range so wide? Sharing this information can help you avoid potential interactions. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). For more information about Injectafers approved uses, see the section Injectafer uses below. There may be drug take-back programs in your area. And this can lead to anemia, including IDA. Drug interactions may change how your medications work or increase your risk for serious side effects. There are currently no generic forms of either drug. Call your doctor for medical advice about side effects. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Your doctor will be able to see how Venofer is working by reviewing your blood tests. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Review our medical disclaimer. This can be very helpful in . Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Call your doctor for medical advice about side effects. Theseside effectsmay last as long as they are undercancer treatment. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Understanding what thoseside effectsare can lead to a strategy to prevent them. weakness. <> One study of just under 5000 HRT users found that 43% were affected. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. Injectafer is a brand-name prescription drug. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. And this could lead to weight gain, if they increase their food intake. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. If you think there has been an overdose, call your poison control center or get medical care right away. There are currently no generic forms of either drug. Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. Before taking Injectafer, talk with your doctor about your health history. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Consult your doctor before breast-feeding. (For more information on Venofer, see the Injectafer vs. Venofer section above). This survey is being conducted by the WebMD marketing sciences department. I used to get a different type but my . Its given by either intravenous (IV) infusion or slow IV injection. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. Injectafer contains the active drug ferric carboxymaltose. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Side effects like nausea and low blood pressure are common with most iron infusions. It is important to get each dose of this medication as scheduled. But some people have a delayed allergic reaction to certain drugs. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. With slow IV injection, the drug is given as a single, slow injection into your vein. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. Cancer patients who have anemia and are taking an ESA. This website is intended for use by US healthcare professionals only. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. (A class of medications describes a group of drugs that work in the same way.). Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. No, Injectafer itself wont make you gain weight. Best food forward: Are algae the future of sustainable nutrition? The drug helps increase your hemoglobin level back to a value thats within the normal range. Drug class: Iron products. Here are answers to some frequently asked questions about Injectafer. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Its possible to get rid of or reduce the severity ofside effects. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. With this condition, you also have a low hemoglobin level. Infusions should be administered over at least 15 minutes. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Other drugs are available that can treat iron deficiency anemia (IDA). Below are examples of these side effects. Throw away unused or expired drugs. Check with your pharmacist if you have questions about the best way to throw out drugs. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. . Do not flush down a toilet or pour down a drain unless you are told to do so. endobj Very bad and sometimes deadly allergic side effects have rarely happened. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Talk to your pharmacist for more details. These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). It can also cause skin irritation and redness. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Diarrhea. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. This means you would get two Injectafer doses of 720 mg each. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Venofer injection contains iron sucrose, a form of the mineral iron. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. (Hemoglobin is a protein thats found inside your red blood cells.). * Sex and gender exist on spectrums. What is the latest research on the form of cancer Jimmy Carter has? In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. What Is the Cost of Whole Genome Sequencing (WGS)? Follow all instructions closely. If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. There are different types of anemia, but IDA is the most common type. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. But you kidneys need iron in order to make EPO. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Read all information given to you. Then the study was split into the following two groups, which are discussed below. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Tell your doctor about the allergy and what signs you had. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Its not currently available in generic form. They can tell you about other medications that may work well for you. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. An iron infusion is a way to increase the body's iron levels quickly. Serious side effects from Injectafer arent common, but they can occur. Serious side effects should be reported to a physician and/or PharmD for medical advice. The information provided is not intended to replace your healthcare provider's medical advice. People in the study received treatment with either Injectafer or Venofer. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. 5 0 obj If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Also tell them about any vitamins, herbs, and supplements you use. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Venofer pregnancy and breastfeeding warnings. chest pain. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. This medication is given by injection into a vein as directed by your doctor. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. You may need extra iron because of blood loss during kidney dialysis. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. In Canada - Call your doctor for medical advice about side effects. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. <> signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. These side effects may include constipation and diarrhea. Otherwise, call a poison control center right away. pain or burning at the injection site. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Potential injection site discoloration has happened. What is Venofer? With anemia, you have a low level of red blood cells (RBCs) in your body. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. "That's why it's so . Details. And theyll recommend how soon after starting the drug you need to have this level checked. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Headache. Procedure Details If you have questions about using Injectafer in a child, talk with your doctor. For some people, it may be OK to continue taking a multivitamin that contains iron. Hemoglobin is a protein thats found in your RBCs. The infusion will take between 15-30 minutes if it is given in. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Always review your medical history with the treatingphysician. But so far I feel better than before the infusion. You should always consult your doctor or another healthcare professional before taking any medication. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. administered at your doctors office or an infusion center. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. The drug helps increase your hemoglobin level back to a value thats within the normal range. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Keep all drugs out of the reach of children and pets. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Together, they can recommend ways to help you manage a body weight thats healthy for you. (A generic drug is an exact copy of the active drug in a brand-name medication.). Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.