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Press J to jump to the feed. Have been able to come off of the beta blocker as my blood pressure and heart rate have dropped back to a low/low normal range. It is a smart investment to get affordable health insurance if you don't already have it. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. I was tested again today my gp ordered that I do will have results later today. Same as sudden weather changes, we get headaches etc. Taking kelp pills, iodine and alcohol drinking after total thyroidectomy. Her overall presentation does not seem to add up in being secondary to urosepsis. Thyroid Problems: Extremes Are Never Good. Upgrade to Patient Pro Medical Professional? Common Methimazole side effects: Drug ineffective: 348 reports Hyperthyroidism (over activity of the thyroid gland): 336 reports Fatigue (feeling of tiredness): 320 reports Weakness: 271 reports Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 262 reports Headache (pain in head): 252 reports My T3 and T4 are at mid to lower end of the range. At my last visit, my Dr suggested seeing if I could wean off my medicine. Solomon B, Wartofsky L, Burman K. Adjunctive cholestyramine therapy for thyrotoxicosis. You pituitary is trying to tell your thyroid to produce more hormones, but the Methimazole (anti-thyroid med) is preventing your thyroid from working. And other symptoms of hypothyroidism. Two weeks ago my tsh was 4.70 then on the 19 th of this month it was 5.02 ref range is 0.34-4.82. Also you will have more definite information when you post on sites like this and we can respond better by knowing this information rather than "my levels are going into the hypo range" we will have your actual levels which makes it better for us to respond. For oral dosage form (tablets): For hyperthyroidism: AdultsAt first, 15 to 60 milligrams (mg) per day, given in 3 divided doses about every 8 hours. upper right abdominal pain. She enjoys giving lectures and writing articles for both the lay public and medical audiences. Helpful - 0 Comment leilajax Gimel is right, it only has a 6 hour half life. Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): Change in taste. If you lack thyroid hormone for a long period of time, you face the risk of a very dangerous condition called myxedema coma, which can ultimately be fatal. His goal is to wean me off very slowly. i have been taking 2.5 mg of methimazole every other day for the past 3 years which is 4x a week and now she told me to just take 2.5mg once a week for 6 weeks and then just stop. Endocrinologic emergencies often fall at the wayside and are not generally considered as a possible diagnosis up front in patients in the emergency department who meet the criteria for systemic inflammatory response syndrome (SIRS). Went back to 10mg, after 2 consecutive blood tests were good (12 weeks) and then went to 7.5, just did a another 12 week stint, all is good so went to 5 mg this week (very happy). I am at 15 MG per weekI take 5 mg on M/W/F and my body is getting used to it but I have passed the two year mark and no signs of it abating. ", Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. I told my endo. IS THERE A WEIGHT LOSS PLAN THAT ADDRESSES THYROIDECTOMY - what do you do to lose weight? Be sure to check with your doctor before you stop taking these medicines. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Methimazole is usually taken every 8 hours. Hello, what you think of my lab results & should I see another doctor? Brand names: Tapazole, Northyx Home Treatment For Low Thyroid: What Essential Oils Are Good For Hypothyroidism? It is not really safe to stop it suddenly. 6 years ago, Nabil N, Miner D, Amatruda J. Methimazole: an alternative route of administration. We strive to reshape medical education and academia in their evolution beyond the traditional classroom. Then I tried one 500 mg capsule and saw how I felt on it beofre I raised it to the dose that was mentioned in the research article. As soon as they see that youre going hyper again, they should put you back on your regular dose. Now I have to start all over again. Other than that, he said that they didn't find anything, such as pneumonia. If you are feeling conflicted about your thyroid medication, discuss your concerns with your doctor. Endometriosis And Thyroid disease: Is There Really A Connection? Yet to you, something does not seem right. Methimazole may also be used for purposes not listed in this medication guide. It is FREE! I'd get night sweats and have trouble sleeping. Most of us feel best with Free T4 at about the mid range point and Free T3 in the upper half to upper third of the range. Your number for what was 2.13? Egton Medical Information Systems Limited. I have been told by every doctor that I've seen in the past few months that it is a serious med, and even though I was only on it for mere months it could have done damage. Methimazole is used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. I was on 5 mg daily and now my dr halved it to 2.5 daily. Then I took 1,000 mg of Regular L-Carnitine and 1,000 mg of Acetyl-L-Carnitine and my TSH just shot right up well into the normal range. While you may experience some symptoms of overactive thyroid more than others, and you may even consider some of them beneficial, it is important to be aware of the strain this condition is putting on your heart, bones, and overall health. Same as sudden weather changes, we get headaches etc. My methimazole was 5 mg once a day. swollen, painful, or tender lymph glands in the neck, armpit, or groin. respect of any healthcare matters. I'm not on meds yet but I agree with AnnLW. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. What was your heart rate when you were at the hospital on Saturday? Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervals. I just have to say thanks for always replying to my posts. and he said that it could not be my thyroid because the Methimazole will be in my blood for 2-3 weeks. I started off with relatively normal levels but my doc found nodules. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. We offer this Site AS IS and without any warranties. Growth of thyroid nodules, increasing goiter size. How should this medicine be used? Didn't find the answer you were looking for? Shaky? We comply with the HONcode standard for trustworthy health information. Make sure you get tested monthly while getting weaned off. How Are Thyroid Disorders Linked To An Increased Risk Of Developing Osteoporosis? My body symptoms were freezing weak cold tired muscles and bones hurt. Common side effects of methimazole may include: This is not a complete list of side effects and others may occur. It is generally well tolerated and has few side effects, but it does require close monitoring because of a low rate of some severe side effects, such as low blood counts. Bartle W, Walker S, Silverberg J. Rectal absorption of propylthiouracil. I don't believe our bodies respond well to abrupt changes. Sometimes it can take a few months to adjust your medication, but the end result is well worth it. yes. Couldn't go outside all summer. You need to be involved in the decisions regarding your care, and how you feel about your medication and its effects are of great importance. You may report side effects to FDA at 1-800-FDA-1088. Ok. Your doctor may occasionally change your dose. If you are feeling unsure about your thyroid medication, it is a good idea to think about the reasons why and to talk about them with your doctor. This exact thing happened to me and then my endo put me back on it and my body couldnt tolerate it I was passing out and my symptoms were so much worse,. I refused to take blood pressure the whole time. If you have thyroid disease and don't take your prescribed medications to manage it, you can have a number of serious long-term effects. You should not breast-feed while using methimazole. Been on Tapazole for 13 months after being diagnosed with graves disease. Good luck, hope you go into remission! :-). Good luck!!! All lab work has come back in normal ranges. Hyperthyroidism can cause unwanted symptoms like anxiety and excessive sweating. (unknowingly had covid at the time of last bloodwork). TSH above 1 is a good place to be in according to my endo. Was there any tapering of the dose at all? Yes, Ive had doctors try to wean me off twice. over a year ago, peace2theworld i teally feel I have late stage chronic lime. ALiEM AIR Series | Orthopedics Lower Extremity Module. If you want to get notified by every reply to your post, please register. To become an empowered patient, you need to obtain a copy of any medical documentation done on you, either lab tests or reports from other physicians and keep your own file so you can see your progresss. I dont think theres any harm in that as long as they are testing your blood frequently like every month. Furthermore, you should fully understand the consequences of untreated thyroid disease. Herpes spreads by oral, vaginal and anal sex. STIs are the most common cause of genital sores. manic bipolar unable to get along with others. It depends how you're feeling bad. It was the Acetyl-L-Carnitine that really worked for me and from other boards seems to work for Graves patients. unable to get any financial help*SSI/DISABILITY DENIED X4, ***this post is edited by moderator *** *** private e-mails not allowed*** Please read our Terms of Use. The third type of carnitine is Proprionyl-L-Carnitine recommended for heart disease. Answer. What Do Herpes Sores Look Like at Different Stages. I am feeling ok just scared that I will be back to where I was 2 years ago, but with Gods help and my awesome doctor I hope that it will be all good. ACMT Toxicology Visual Pearl: Swollen Lips, PECARN Pediatric Head Trauma: Official Visual Decision Aid, A Starters Roadmap to EM Resources: Books, Websites, and Apps, D50 vs D10 for Severe Hypoglycemia in the Emergency Department, The Dirty Epi Drip: IV Epinephrine When You Need It, Tips for Interpreting the CSF Opening Pressure, Trick of the Trade: Mix Ceftriaxone IM with Lidocaine for Less Pain, Trick of the Trade: Urine Pregnancy Test Without Urine, Wellness and Resiliency during Residency: EM is a career with unresolved stories, Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License, Academic Life in Emergency Medicine - All Rights Reserved (except for the PV Cards and MEdIC Series PDFs), Block the production and release of thyroid hormone (preventing the opposing team from getting the ball and scoring), Block the sympathetic outflow (preventing the soccer ball from going out of bounds), Block peripheral conversion of T4 to T3 (preventing penalty kicks), Mechanism of action: Inhibit thyroid peroxidase, an enzyme involved in the production of T3 and T4 through the iodination of tyrosine residues on thyroglobulin, Agents: propylthiouriacil (PTU) and methimazole (MMI), No head-to-head trials have shown any benefit of using one thionamide over another in the management of thyroid storm. Slept all day, terrible itching skin especially at night while trying to sleep. rachelemacd So I now went to Winthrop Hospital and am off 5 mg of methimazole since I'm taking the nuclear test this week. Treatment of hyperthyroidism with a combination of methimazole and cholestyramine. ALiEM is your digital connection to the cooperative world of EM. over a year ago. You should not breast-feed while using this medicine. Didn't find the answer you were looking for? I started out at 30mg a day. Thanks, THANKS FOR YOUR HELP LET ME KNOW IF YOU THINK OF ANYTHING. Each time I reduce, my TSH elevates- but my T3 stays within range which is what my endo focuses onand it does take about six weeks for my body to adjust to the lower dosebut it does adjust. Said it was controversial. and Privacy Policy and steps will be taken to remove posts identified It is also used before thyroid surgery or radioactive iodine treatment. with 87 to 100 percent becoming euthyroid within a few weeks to a few months . Saturday evening, I took my blood pressure, and the systolic reading was over 200. I was taken to jail where I was geld for two weeks without my medicine and let me tell you I got sick with peripheral edema, vasculitis. Maintenance dose: 5 to 15 mg orally per day. over a year ago, Glorrie Do not take extra medicine to make up the missed dose. 0.84 t4 sounds pretty low so maybe that was part of the decision? Stop using methimazole and call your doctor right away if you have signs of infection such as: sudden weakness or ill feeling, fever, chills, sore throat, cold or flu symptoms; painful mouth sores, pain when swallowing, red or swollen gums; or. Side effects are also most likely to occur within the first three months of treatment, so keep that in mind if you are beginning a new regimen. fatigue and hyperthyroidism and Graves' Disease. Copyright 1996-2023 Cerner Multum, Inc. I tapered and stopped completely and felt so good. If you need surgery, tell the surgeon ahead of time that you are using methimazole. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. I remember being on armour thyroid. Do not use methimazole in larger or smaller amounts or for longer than recommended. And there are no natural substitutes for antithyroid medications, either. Do not give this medicine to a child without medical advice. It is also taken before thyroid surgery or radioactive iodine therapy. Usual Pediatric Dose for Hyperthyroidism: Initial dose: 0.4 mg/kg orally per dayMaintenance dose: 0.2 mg/kg orally per day (approximately half the initial dose) Comments: Daily doses are usually given in 3 divided doses at approximately 8 hour intervals. Tell your doctor if you are pregnant or if you become pregnant while using this medicine. Birth defects an option due to untreated Graves' disease? A previous ALiEM blog post further discusses some of the nuances associated with the diagnosis of thyroid storm. Skipping or stopping your antithyroid medication or thyroid hormone replacement will lead to undesirable and possibly dangerous effects. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. If the patient is given PTU during treatment of thyroid storm, this should be switched to methimazole at the time of discharge unless methimazole is contraindicated. My gut feeling is that this method seems to make greater ense than the shock and confusion of going 'cold-turkey'. Increased pain. I have been taking the same dosages for all those years, except my dosage for Methimazole was brought down to 1 and 1/2 pills (5 mg pills) about a year ago. Not taking your hypothyroid or hyperthyroid medication can cause undesirable, dangerous, and even life-threatening conditions, ranging from fatigue and changes in blood pressure to death. National Institute of Diabetes and Digestive and Kidney Diseases. Vancomycin Loading Doses in Pediatric Patients: A Missed Opportunity? Got dosage down to 5mgs. over a year ago. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. Im feeling exactly those symptoms minus the weight loss because that hasnt changed on 2.5. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. Methimazole is an antithyroid medicine. Weaning off of Methimazole What next? It can also increase the risk of developing a dangerous condition known asthyroid storm, which has a high fatality rate. I don't believe our bodies respond well to abrupt changes. Get your TBII or TRAb antibodies tested for Graves, anti-TPO and TGAb for hashimoto's. I just watched my diet, no red meat, no sugar, no wheat or dairy, and room temp water. Swollen hands, feet, and face. So I would gradually reduce until you think you can go cold turkey. We tapped the CDC for information on what you need to know about radiation exposure, Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them. I am a 52 year old female and I had been on 15MG Methimazole for the over 2 months and my Endo lower the dosage to 10MG (took the And I vote you find another endo even if you do even out - you want someone who knows their stuff to monitor you in case you relapse in the future. The problem can be changing your diet, as you don't know how the thyroid will react to this. I'll hold the cetyl L-carnitine and start with L-Carnitine then. By using this Site you agree to the following, By using this Site you agree to the following. Some my symptoms inc My thyroid was stable for about 4 years, then suddenly, after my Mom's death, my thyroid went into hypothyroid. I would ask to do labs again. About Us Our Team Annual Report Our Culture Contact Disclosures, ALiEMU ALiEM Cards Chief Resident Incubator Faculty Incubator Wellness Think Tank, ACEP Annals of Emergency Medicine EBSCO Health-DynaMed Plus Essentials of Emergency Medicine SAEM The Teaching CoOp US Acute Care Solutions Western Journal of Emergency Medicine. I should have listened to him. pale skin, easy bruising, unusual bleeding. Is there side effects from stopping or withdrawal symptoms? We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Previous: "Why Wasn't I Taught This Stuff In Medical School?" Yet many hypo sufferers complain of it as well. Try our Symptom Checker Got any other symptoms? If the hyperthyroidism returns, the antithyroid drugs are re-started. Your phone, computer, or another alarm can be programmed to give you a daily reminder. :), The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Have been on it for 18 months. Tell your doctor about all your current medicines and any you start or stop using, especially: a blood thinner--warfarin, Coumadin, Jantoven; or. Its been almost a month now on the 2.5 so Im going to get the blood work rechecked within a week or so. Medically reviewed by Drugs.com on Feb 20, 2023. Hi Rachel, are you finally off the methimazole? Treatment and prognosis of Graves disease in children and adolescents. This is perfect for me. My blood pressure was constantly high until I was off of medications. I hadn't tested much in over a year- hoping this prior post link will work on this post to refresh anyone's memory who cares to 27M, 6'0, 174lb, Been on NP for about 4 months, Don't smoke or drink. Diabetes Tests And Diagnosis: What To Expect During Your Medical And Physical Examinations? The first time my Endo told me to decrease my dose from 10 mg to 5 mg, about 2 weeks after I did that I got a rebound effect of symptoms so I raised it by 2.5 mg and told her. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Your story is exactly like mine. They told me to do that when I was taking 4 pills a day (20 mg) to get a test. It bounced around .53 to .25 then .50 again but never above. You should not use methimazole if you are allergic to it, or: To make sure methimazole is safe for you, tell your doctor if you have: Using methimazole during pregnancy could harm the unborn baby. We offer this Site AS IS and without any warranties. Call your doctor at once if you have: liver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). An EKG is ordered, revealing an irregularly irregular rhythm, and an urinalysis is conducted, showing many bacteria. Constipation. She seems relatively anxious on physical exam, and you note that she is diaphoretic. Posted My tsh leve as of yesterday dropped down to 3.65 so I'm in range again ref range is 0.34-4.82. But have plenty of lab slips on hand and get checked if you feel like hurting someone. It also offers solutions for some of the common reasons why people quit their thyroid medication, and what to consider if you feel like stopping yours. How long were you on Methimazole before weaning off? Store at room temperature away from moisture and heat. Severe hyperthyroidism: 60 mg orally per day. Unfortunately, there isn't a natural or herbal replacement for thyroid hormone. These side effects usually mimic the side effects of hypothyroidism, because if you stop taking your medication your body will not be able to produce it naturally for some time. Patient does not provide medical advice, diagnosis or treatment. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. My Endocrinologist has started weaning me off of Methimazole. I'd never stop any medication cold turkey. unusual tiredness or weakness. The maintenance dose is 5 to 15 mg per day. Found that I could not take vitamin D pills, that they had to be the gel caps. Take your doses at regular intervals to keep a steady amount of the drug in your body at all times. I got diagnosed with graves approx 1 year ago I responded good to tapazole however I was sick with a cold and forgot to take my meds for like a week? Sometimes though if your levels are too far out of range (hypo) it is necessary to stop the meds temporarily and then restart them. Some of the effects of skipping or stopping your thyroid medication are obvious, while others are so subtle they can go undiagnosed for years. 2013 Nov;31(4):969-86. Paying for medications can be stressful. appropriate medical assistance immediately. This required my Endo to make a lot of lowering adjustments and I adjusted my carnitine dosages. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The question is now . What Do Herpes Sores Look Like at Different Stages. I am weaning off methimazole i was only taking 10 mg a day down to 7.5 mg for 2 weeks feeling lightheaded and was wondering if anyone knew of any side effects? Again, be sure to discuss any concerns with your doctor and do not stop taking your medication without consulting with them first. Hodak S, Huang C, Clarke D, Burman K, Jonklaas J, Janicic-Kharic N. Intravenous methimazole in the treatment of refractory hyperthyroidism. Reddit and its partners use cookies and similar technologies to provide you with a better experience. I was diagnosed with Autoimmune Hyperthyroidism in Dec., 2006. Thank you, {{form.email}}, for signing up. You will learn what these results mean very quickly and you can always learn more about them online. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. However, since starting to wean off, my numbers have gotten closer to the Hyper T side again. Even while I was having a thyroid storm and my hr was way to high it took the doctor telling me I was going to die before I let him give me meds to slow my heart. Thyroid medications usually do not work right away. I tried this and my TSH rose from less than 0.001 (where it had been for 2 years) to 0.12 (in the right direction but not enough). Hashimoto patients do better on the Regular L-Carnitine. She also tells you that she has had recent blood work ordered by her primary care physician that was highly suspicious for some sort of thyroid disorder, but the results have not been made known to her yet. first cutting the 5mg tablet in half then in 1/4's. I feel fine. People with Hashi's are extremely sensitive to both the thyroid-blocking meds and the thyroid hormone replacement meds. Takiing Armour (thyroid hormone replacement) has seemed to cause your hyperthyroidism. When I started getting hyper symptoms from armour I tapered slowly and went off but my TSH never sprang back. Her vital signs are blood pressure of 184/106 mmHg, heart rate of 130 beats per minute, respiratory rate of 22 breaths per minute, and temperature of 102.7F. Serious and sometimes fatal infections may occur during treatment with methimazole. Coming off of Klonopin after 8 monthswhat to expect and how to do so, Graves Disease/hyperthyroid & I experience Hypnagogic hallucinations-anyone with similar experie, Thyroid Removal Effects and Graves Disease. There are 3 kinds of L Carnitine suppslements what kind did you take to help? Well, nothing like wasting money for an antiquated panel is there? I hope you go into remission and you dont have to keep taking those god forsaken meds. A relatively low dose of Methimazole was prescribed, along with Lisinopril, and Metoprolol. Should I stop Methimazole over a high TSH? The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. We recommend using methimazole (MMI; 0.25 to 1.0 mg/kg per day). In the case of our patient above, both laboratory parameters and the overall clinical picture confirm our suspicion of thyroid storm. The achy legs suggests you may be carnitine deficient, also vitamin D deficient and Magnesium deficient and these things are extremely important for thyroid patients. Mine endo only did it once every 6mo and within that time my tsh was no longer detectable and I got super super sick. The risk of serious side effects due to thyroid medication is extremely smallfar lower than the risks of remaining untreated. Were the tests TRab or TSI run to make sure your Graves antibodies were low before it was stopped? However, since starting to wean off, my numbers have gotten closer to the Hyper T side again. Burch H, Wartofsky L. Life-threatening thyrotoxicosis. Could you be swinging back into hyperthyroid? I think its common to wean off after being in normal range for 12-18 months to see if its gone into remission, thats what my endocrinologist did the first time my graves was diagnosed. I DONT KNOW IF I COULD STILL BE HYPER.MY LAB RESULTS HAAVE BEEN NORMAL FOR 1 YEAR. We offer this Site AS IS and without any warranties. Stomach/digestive issues (gassy feeling/bloating), depression and fatigue are certainly hypo symptoms, but many people who are hyper have them as well. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Some thyroid medications can also cause hair loss, which most people find frustrating and undesirable. Please get back to me.. All lab work has come back in normal ranges. I just wanted to tell everyone DON'T GIVE UP and DON'T TAKE THE RADIATED IODINE or have your thyroid removed (unless there is a growth of course). Best, Rachel. Talk to your doctor about these issues, as they can be the effects of your thyroid hormone levels getting back to normal. I am a 52 year old female and I have been on 15MG Methimazole for the over 2 months and Endo lower the dose since my result for Tr Hi, By learning about your labs and what they mean and following your body symptoms, you will have more information and be more prepared for discussions with your physician. Diagnosis of thyroid storm can be somewhat of a challenge because of this, but a scoring system developed by Burch and Wartofsky 1 can assist in determining the likelihood of thyroid storm in patients based on presenting signs and symptoms. Sounds like your doctor wants to work with you though if he gave you that choice. (PTU), Methimazole, or Tapazole thyroid medicine 4 days before their tests. Methimazole doses are based on weight in children, and any changes may affect your child's dose. 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